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Latest hypertension News By Ernie Mundell and Robin Foster HealthDay ReportersFRIDAY, Oct where to buy diuretic lasix. 15, 2021 Mirroring a similar recommendation issued last month for the Pfizer hypertension medications treatment, an expert advisory panel to the U.S. Food and Drug Administration on Thursday recommended a half-dose booster shot of the Moderna treatment be given to certain recipients six months after their second shot. Panelists recommended that everyone aged 65 or older who received the two-dose Moderna regimen get a third dose, as well as any younger adult who might be at high risk for hypertension medications due to a medical condition or a job that increases their exposure to where to buy diuretic lasix hypertension, The New York Times reported. The FDA is not obligated to follow its advisory panels' decisions, but it typically does.

The data presented was not particularly decisive, committee members said, but they noted that a precedent had been set in September when the FDA gave emergency authorization to booster shots for the millions of Americans who'd gotten the Pfizer-BioNTech treatment. The evidence of a need for booster shots was clearer for the Pfizer treatment, however where to buy diuretic lasix. In data presented to the panelists last month, one study from the U.S. Centers for Disease Control and Prevention found that four months after a person's second dose of the Pfizer treatment, its effectiveness in preventing illness requiring hospitalization fell from 91% to 77%. But with the Moderna treatment, the drop-off over time was much less dramatic, making where to buy diuretic lasix the justification for any booster shot much weaker.

Acknowledging that, Moderna argued instead that a booster could still be useful in preventing mild or moderate forms of hypertension medications. As part of the data presented, Moderna said its study found that antibody levels to hypertension rose by 1.8 times after people received a booster shot. But the company narrowly missed another where to buy diuretic lasix threshold set by the advisory panel. The committee hoped to see a fourfold increase in neutralizing antibodies in 88.4% of study participants who got boosters, but the Moderna study observed such a rise in 87.9%, the Times reported. One expert in infectious disease was dubious that boosters for younger, healthier Moderna treatment recipients are necessary.

"The key question to focus on is whether there is evidence of erosion of protection against hospitalization with hypertension medications," said where to buy diuretic lasix Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, in Baltimore. "In those age or risk groups where this has occurred, a booster may be warranted." However, he said that "it is unclear what benefit those at low risk for hospitalization gain from a booster, as there is not enough data to show that boosters protect for a significant amount of time against mild breakthrough s." Adalja said that's especially true for the Moderna product, "as it has been associated with less waning [of protection] than other hypertension medications treatments." Millions of Americans who got the Moderna and Johnson &. Johnson hypertension treatments have had to watch those who received the Pfizer treatment roll up their sleeves for where to buy diuretic lasix a booster shot, wondering when they will get the same chance at extra protection. Now that the FDA advisors have made their recommendation, the agency will make its decision on whether to authorize boosters for at least some people who were immunized with the Moderna treatment.

If the FDA approves the extra dose, a panel convened next week by the U.S. Centers for Disease Control and Prevention will then recommend more specifics where to buy diuretic lasix on who should get them. As a final measure, the CDC panel's decision has to be approved by Dr. Rochelle Walensky, director of the U.S. Centers for Disease where to buy diuretic lasix Control and Prevention.

One of the trickier points before the advisory panel was the dosage of any Moderna booster. The two initial Moderna shots contain 100 micrograms of treatment each. But the drugmaker said in documents filed with the FDA that 50 micrograms ought to be enough where to buy diuretic lasix for a booster for healthy people. A company study of 344 people gave them a 50-microgram shot six months after their second dose, and levels of lasix-fighting antibodies jumped. Moderna said the booster even triggered a 42-fold rise in antibodies able to target the highly contagious Delta variant.

Side effects were similar to the fevers and aches that Moderna recipients commonly experience after where to buy diuretic lasix their second regular shot, the company said. On Friday, the same advisory panel will issue its recommendation on whether booster shots are needed for the roughly 15 million Americans who received the one-dose Johnson &. Johnson treatment, which has shown significant weakening in effectiveness over time. The panel will also look into the safety and effectiveness where to buy diuretic lasix of mixing and matching different brands of treatment, something regulators have not endorsed so far. In a study published Thursday on a non-peer-reviewed site, data suggested that people who'd gotten the Johnson &.

Johnson treatment might get a bigger bump in protection if their second dose is either the Pfizer or Moderna shot, rather than a second dose of J&J. Beyond the where to buy diuretic lasix question of waning efficacy of hypertension medications treatments, some experts say there is also a need to "harmonize" the country's booster strategy. "We're in this very complicated situation right now. People are going into pharmacies or places where treatments are available and saying, 'I want my third dose of Moderna,' or 'I want my second dose of J&J,'" Dr. H.

Cody Meissner, an infectious disease expert at Tufts Medical Center in Boston, who serves on the FDA advisory panel, told the Times. "I don't think anyone has much doubt that we will need a booster dose for these treatments. What we don't know is. How urgent is the need?. " An estimated 103 million Americans are now fully vaccinated with Pfizer's formula, 69 million with Moderna's and 15 million with J&J's, according to the CDC.

Regulators took up the question of Pfizer boosters first because the company submitted its data ahead of the other treatment makers. As for people who got the J&J treatment, the company has submitted data to the FDA for two different options. A booster shot at two months or at six months. The company said in its FDA submission that a six-month booster is recommended but that a second dose could be given at two months in some situations, the Associated Press reported. J&J released data in September showing that a booster given at two months provided 94% protection against moderate-to-severe hypertension medications .

The company has not disclosed patient data on a six-month booster, but early measures of lasix-fighting antibodies suggest it provides even higher protection. Even without a booster, J&J says, its treatment remains about 80% effective at preventing hypertension medications hospitalizations. Scientists emphasize that all three treatments still offer strong protection against severe disease and death from hypertension medications. The thorny issue is how quickly, and how much, protection against milder may wane. More information Visit the U.S.

Food and Drug Administration for more on hypertension medications treatments. SOURCES. Associated Press. The New York Times. Amesh Adalja, MD, senior scholar, Johns Hopkins Center for Health Security, Baltimore Copyright Â© 2021 HealthDay.

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Latest Neurology browse around these guys News By lasix price per pill Alan Mozes HealthDay ReporterTHURSDAY, Oct. 28, 2021 (HealthDay News) -- The number of Americans who are dying from Parkinson's disease has jumped by 63% in the past two decades, new research shows. The fresh analysis also revealed that men face double the risk of lasix price per pill dying from the progressive and incurable disease than women.

A notably higher death rate was also seen among white people, as compared with peers of other racial/ethnic backgrounds. "The message is straightforward," said study author Dr. Wei Bao lasix price per pill.

"This study showed that an increasing number of people died from Parkinson's disease during the past 20 years, and this cannot be simply explained by population aging." Bao is an associate professor in the department of epidemiology at the University of Iowa's College of Public Health, in Iowa City. He and his colleagues published their findings online Oct. 27 in the lasix price per pill journal Neurology.

According to the Michael J. Fox Foundation, Parkinson's affects roughly 1 million Americans and more than 6 million people around the world. To get a handle on trends among Parkinson's patients, Bao and his colleagues analyzed lasix price per pill data collected by the U.S.

National Vital Statistics System. The team found that nearly 480,000 Americans died of Parkinson's between 1999 and 2019. During that time, the risk of dying from Parkinson's rose year after year by an average of 2.4%, with a significant increased risk seen among both men and lasix price per pill women of all ages and ethnicities, and across both urban and rural locales, and in every state in the nation.

That steady rise translated into nearly nine out of every 100,000 Americans succumbing to Parkinson's by 2019. That figure is notably up from a little more than five Parkinson's deaths for every 100,000 Americans just 20 years earlier. While risk went up across the board, men appeared to be much more vulnerable than lasix price per pill women, the findings showed.

By 2019, the death rate among men was pegged at double that of women. One possible reason why. Higher levels of estrogen in women may ultimately bolster motor lasix price per pill control, the investigators said, and shield women from developing Parkinson's.

Death rates were also cited as being highest among white patients (9.7 per 100,000 people), followed by Hispanics (6.5 per 100,000) and Black people (4.7 per 100,000). The team cautioned, however, that some of that differential might reflect higher diagnosis rates among whites due to greater access to neurology care. As to what might be driving up death rates overall, the study authors stressed that their research did not set out to identify lasix price per pill cause, with Bao acknowledging that "the reason is not clear at present and warrants further investigation." But the team theorized a number of possibilities.

On the one hand, a higher death rate among Parkinson's patients may be at least partially linked to a rising risk for developing Parkinson's in the first place. And investigators pointed to a variety of reasons Parkinson's may be becoming more common, including worsening environmental factors such as elevated exposures to pesticides, heavy metals, air pollution and herbicides. Improved accuracy on precise cause of death (as noted lasix price per pill on death certificates) may also have played a role, the investigators added.

Still, James Beck, chief scientific officer for the Parkinson's Foundation, said the findings "are not surprising." The foundation has also observed that the number of people with Parkinson's has risen, and "will continue to rise as the population ages, so an increase in mortality rates would be expected," he noted. Beck said that improved diagnostics is what accounts for much of the rising death rates, as doctors become more adept at recognizing Parkinson's, "which would lead to higher rates of identifying PD [Parkinson's disease] as a cause of death." Regardless, Dr. Rachel Dolhun, senior lasix price per pill vice president of medical communications at the Michael J.

Fox Foundation, suggested that while "more data is needed to better understand these trends," Parkinson's patients should not be discouraged by the numbers. "If you're a person lasix price per pill or family living with PD, I understand how a headline like this could be scary," she said. "But the bottom line is that these types of studies are helping us direct more resources and research so that we can learn more about the disease and its impact on the community, develop better treatments and a cure and, ultimately, prevent Parkinson's." Meanwhile, "I often tell people â especially those newly diagnosed â that your Parkinson's is your Parkinson's.

Your symptoms, how they change over time, and how they impact your life are all unique to you," Dolhun added. "The individualized nature of the lasix price per pill disease can make it difficult to predict progression and symptoms in any one person." So, she said, the goal is "to manage the disease and live as well as possible," through a combination of diet, exercise and good physician guidance, because "for many, Parkinson's doesn't significantly shorten lifespan." More information There's more on Parkinson's at the Michael J. Fox Foundation.

SOURCES. Wei Bao, MD, PhD, associate professor, department of epidemiology, College of lasix price per pill Public Health, University of Iowa, Iowa City. James Beck, PhD, chief scientific officer, Parkinson's Foundation, Miami.

Rachel Dolhun, MD, senior vice president, medical communications, Michael J. Fox Foundation, lasix price per pill New York City. Neurology, Oct.

Alzheimer's Disease and Aging Brains See SlideshowLatest Women's Health News By Cara Murez HealthDay ReporterTHURSDAY, Oct. 28, 2021 lasix price per pill (HealthDay News) Might breastfeeding affect a new mother's future brain health?. That's the intriguing question posed by a new study that flips the narrative from the often-touted benefits for baby to what impact breastfeeding might hold for Mom years later.

Researchers from UCLA Health found that women over age 50 who had breastfed their babies performed better on tests of brain function than those who had not. "The findings lasix price per pill were pretty straightforward in that we compared women who did versus did not breastfeed," said lead author Molly Fox, an assistant professor in the Departments of Anthropology and Psychiatry and Behavioral Sciences at the University of California at Los Angeles. And women who did performed better on tests of thinking and memory skills, also known as cognition.

The findings are significant because impaired cognition after age 50 can be a strong predictor of Alzheimer's disease, the leading form of dementia and cause of disability in the elderly. About two-thirds lasix price per pill of Americans with Alzheimer's are women. "We repeated the analyses looking only at women who had children to make sure that we weren't just picking up an effect of whether or not you had children and the results were the same," Fox said.

"It does seem to be that there was something connected to breastfeeding specifically, and not just whether or not you have kids." The study included 115 women who were part of two 12-week clinical trials at UCLA Health. Sixty-four described themselves as depressed, and 51 as lasix price per pill not depressed. All completed a questionnaire about their reproductive life history, including the age they began their period, number of pregnancies, length of time they breastfed for each child and their age at menopause.

The women also completed psychological tests that measured brain function in four areas. Learning, delayed recall, executive functioning and processing lasix price per pill speed. None had been diagnosed with dementia.

In all, 65% of women who said they were not depressed had breastfed, compared to about 44% of women lasix price per pill with depression. Whether they described themselves as depressed or not, women who had breastfed performed better in tests of all four brain functions evaluated compared to those who had not, the study found. All four scores were significantly linked to breastfeeding in women without depression.

But only two were strongly associated with breastfeeding in the group lasix price per pill with depression -- processing speed and executive function, which includes skills such as flexible thinking, self-control and working memory. Women who had not breastfed had significantly lower scores in three of the four brain functions evaluated compared to women who had breastfed for one to 12 months. Additionally, their scores were lower in all four areas compared to women who breastfed for more than a year.

What's unique about breastfeeding Though the lasix price per pill researchers weren't able to directly examine what's connecting the two, they have some theories. "I think it would make sense that there are some things that we know breastfeeding affects, like a woman's energy metabolism, lipid metabolism, and these are systems that are already implicated in brain aging and Alzheimer's risk," Fox said. The intriguing -- and exciting -- possibility is that breastfeeding could exert effects on metabolism or other bodily functions that could be responsible for the pattern researchers saw.

"To address the question about what it means for women who did or did not have kids, the story is much more complex than the scientific study, because the actual lived experience in women's reproductive histories involves so many different phases and systems and we were only looking lasix price per pill at this one factor," Fox said. She noted that the study shows an association and doesn't prove cause and effect. QUESTION Newborn babies don't sleep very much.

See Answer The lasix price per pill link might not even have a biological cause, Fox said, but might owe to the psychological or social experience of bonding with your child or the family dynamics around breastfeeding. Dr. Neelum Aggarwal, a fellow of the American Academy of Neurology and associate professor at Rush Medical College in Chicago, reviewed the findings.

"This is an interesting study as it expands our thinking about a woman's reproductive history and relatedness to lasix price per pill cognitive decline and dementia," she said. But more study is needed, Aggarwal said. Multiple factors and issues in society, including concerns about mood, depression, anxiety and how they may limit breastfeeding, should be investigated in a larger, diverse population, she said.

Dr. Nicole Smith, medical director at the Maternal-Fetal Medicine Clinic at Brigham and Women's Hospital in Boston, said breastfeeding can provide lifelong benefits to a mother's health. Among them are lowering her risk for heart disease, diabetes and breast cancer.

Smith said the relationship between mental decline and breastfeeding may be related to those other factors. "Whether or not a woman breastfed, however, is unlikely to be the most important variable in maintaining cognitive function," she said. "A healthy lifestyle, including optimizing cardiovascular health, is most likely to be beneficial." In her practice, Smith said she aims to help women achieve their breastfeeding goals -- whatever they may be.

"Certainly we can have healthy babies and mothers when babies are formula-fed," she added. The findings were recently published in the journal Evolution, Medicine, &. Public Health.

More information The U.S. Department of Health and Human Services Office on Women's Health has more on breastfeeding. SOURCES.

Molly Fox, PhD, assistant professor, Departments of Anthropology and Psychiatry and Behavioral Sciences, University of California at Los Angeles. Neelum Aggarwal, MD, associate professor, neurological sciences, Rush Medical College, Chicago, and neurologist, Rush Alzheimer's Disease Center, Chicago. Nicole Smith, MD, MPH, medical director, Maternal-Fetal Medicine Clinic, Brigham and Women's Hospital, Boston.

All rights reserved. From Parenting and Newborn Resources Featured Centers Health Solutions From Our SponsorsLatest Senior Health News By Amy Norton HealthDay ReporterTHURSDAY, Oct. 28, 2021 (HealthDay News) ADHD medications are increasingly being prescribed to older adults, and they may cause a short-term spike in the risk of heart attack, stroke and arrhythmias, a large new study suggests.

Stimulant medications, such as Ritalin, Concerta and Adderall, are commonly used to treat attention deficit hyperactivity disorder (ADHD). But they are also increasingly being prescribed "off-label" to older adults, to combat conditions such as severe drowsiness, appetite loss and depression. The new findings add to evidence that the drugs can pose heart risks.

Researchers found that on average, older adults starting on a stimulant showed a 40% increase in their risk of heart attack, stroke or ventricular arrhythmia within 30 days. Ventricular arrhythmias are rhythm disturbances in the heart's lower chambers, and some can be fatal. In the study, stimulant users had double the risk of dying within a month of starting a stimulant, compared to older adults who were similar in terms of health but not using a stimulant.

The absolute risks were relatively small, said lead researcher Mina Tadrous, an assistant professor of pharmacy at the University of Toronto. Over one year, 5 out of 100 stimulant users had a heart "event," the study found. That compared with between 3 and 4 of every 100 non-users.

And the increased risk appeared limited to the first 30 days of use, Tadrous said. Over the longer term -- six months and one year -- stimulant users were not at greater risk of heart trouble. Why?.

It's not clear, but Tadrous said it may be because of monitoring. Doctors have long known that stimulant medications can raise blood pressure and heart rate. In fact, the drugs carry warnings about those effects, particularly for people with established heart disease.

So doctors and patients are likely checking for red flags -- a spike in blood pressure or symptoms like chest palpitations -- and if they come up, the drug may be stopped, Tadrous explained. Over the longer term then, older adults who remain on stimulants may be those who are less likely to have heart and vascular side effects. For the study, Tadrous and his colleagues looked at data on more than 30,000 adults over 65 living in Ontario, Canada.

The group included more than 6,400 patients who started a stimulant prescription between 2017 and 2019. Researchers compared each of those patients with four others who were similar in terms of health and demographics but were not prescribed a stimulant. The stimulant medications included amphetamine, dextroamphetamine (brands such as Dexedrine and ProCentra), methylphenidate (Ritalin, Concerta and other brands), and lisdexamfetamine (Vyvanse).

On average, older adults prescribed stimulants were 40% more likely to land in the emergency room or be hospitalized for a heart complication within 30 days. IMAGES Heart Illustration Browse through our medical image collection to see illustrations of human anatomy and physiology See Images The sharpest increase was in the risk of ventricular arrhythmia, which was three times higher compared with other older adults. For patients already on stimulants, Tadrous said the lack of longer-term excess risks could be seen as reassuring.

But, he said, doctors should remain "vigilant" in monitoring blood pressure and other markers of heart health in those patients. Dr. James Kirkpatrick is chair of American College of Cardiology's Geriatric Cardiology Section Leadership Council.

He said the lack of longer-term risks was the most interesting finding from the study. It's not clear why that is, Kirkpatrick said, but he agreed that patient monitoring might explain it. Kirkpatrick, who was not involved in the study, noted that for some older adults, the symptoms for which stimulants are prescribed can be so debilitating, the potential for heart effects could be worth the benefits of treatment.

"Individual patients have individual needs," he said. "It's always about balancing the benefits and risks." Older adults already on a stimulant should not stop taking it on their own, Kirkpatrick advised. If they have concerns, he said, they should talk to their doctor.

Kirkpatrick agreed that ongoing monitoring is important. And ideally, he said, older adults should regularly have a medication "review" with their doctor, to talk about which drugs they still need and where a change might be better. The findings were published Oct.

25 in JAMA Network Open. More information The American College of Cardiology has more on the safety of stimulant medications. SOURCES.

Mina Tadrous, PharmD, PhD, assistant professor, pharmacy, University of Toronto, Canada. James Kirkpatrick, MD, chair, Geriatric Cardiology Section Leadership Council, American College of Cardiology, Washington, D.C., and professor, medicine, University of Washington Medical Center, Seattle. JAMA Network Open, Oct.

28, 2021 (HealthDay News) The U.S. Centers for Disease Control and Prevention announced Thursday that it has lowered its limits for lead poisoning in kids. The move is expected to more than double the number of 1- to 5-year-olds with worrisome levels of the toxic metal in their blood, according to the Associated Press.

That means the number is projected to grow from 200,000 to about 500,000, AP said. "Lead exposure at all levels is harmful to children and can be detrimental to their long-term health," CDC Acting Principal Deputy Director Dr. Debra Houry said in a news release.

"Protecting the health and well-being of children as they grow and develop is of the utmost importance, and I am confident this update will allow us to further safeguard the health of the next generation." The new level updates the CDC's blood lead reference level (BLRL) from 5Âµg/dL to 3.5 Âµg/dL. The CDC last changed its definition nine years ago and had pledged to consider an update every four years. But work on a revision hit snags during the Trump administration, Patrick Vreysse, head of the CDC's National Center for Environmental Health, told the AP.

With the change, the CDC encouraged federal partners, health departments, health care providers and others to focus resources on kids with the highest blood lead levels. The aim is to reduce kids' lead levels, lower their health risks, and identify and eliminate sources of lead exposure. While the CDC said overall blood lead levels have declined, lead exposure remains a significant public health concern for some children because of persistent lead hazards.

Sources include lead-based paint, contaminated soil, household plumbing materials, contaminated food and candies, consumer products and lead dust from workplaces that's brought home on caregivers' clothing. At very high levels, it can damage organs and cause seizures, the AP reported. Black children, those living in low-income households, and those who are immigrants or refugees are more likely to live in neighborhoods where lead is pervasive, the CDC said.

It noted that no safe blood lead level in children has been identified and even low levels of lead in blood have been shown to affect learning and academic achievement. Some effects may be permanent. More information Learn more about symptoms and treatment of lead poisoning at the Mayo Clinic.

SOURCES. U.S. Centers for Disease Control and Prevention, news release, Oct.

SLIDESHOW The 14 Most Common Causes of Fatigue See SlideshowLatest Depression News By Cara Murez HealthDay ReporterFRIDAY, Oct. 29, 2021 (HealthDay News) When Tommy Van Brocklin signed up for a trial of a special type of magnetic brain stimulation therapy that could potentially ease his depression, he had already been living with the mood disorder for 45 years. Van Brocklin, 60, first underwent an MRI that located the part of his brain that regulates executive functions such as problem-solving and inhibits unwanted responses.

Then for five days, for 10-minute sessions 10 times each day, doctors used repeated pulses to stimulate the part of his brain that could impact his depression. "I was kind of at the end of my rope, very frustrated with it all," Van Brocklin said about how he felt before trying the treatment. "I never knew when it was going to be a good day and when it was going to be a bad day.

Just could never get on top of it, you know?. Well, maybe I would for a while and then it would go right back into it." While at first Van Brocklin noticed no change, by day two he felt emotional and by day three he could tell it was working in a way that medications and talk therapy no longer did for him. "The third day, I guess it kicked into gear, and I started to get better and better and better," Van Brocklin said.

"The treatment seems to show me that there is enjoyment in everyday things, the small things, like walking my dog just for the enjoyment of it, or playing my guitar for the fun of it." The treatment, called SAINT, is an intensive, individualized form of transcranial magnetic stimulation (TMS). In the new trial, researchers worked with 29 individuals who had severe depression that was resistant to other treatments. About half of the participants received SAINT.

The other half had a placebo that was meant to mimic the real treatment with a magnetic coil that felt like a magnetic pulse The relief came quickly, within days, and was successful for 78.6% of the treatment group. They were found to be no longer depressed in standard evaluations. Side effects were temporary fatigue and headaches.

Study author Dr. Nolan Williams, an assistant professor in the Department of Psychiatry at Stanford University, was motivated to provide a quicker solution for people who had psychiatric emergencies. The solution would also be an alternative to electroconvulsive therapy, which is used by only about 1.5% of people to treat a suicidal depressive episode for a variety of reasons, he said.

New treatment could work faster in emergencies "The vast majority of people who come in with suicidal depression in the United States, into U.S. Psychiatric hospitals, don't have access to any sort of emergency intervention. That's coupled with the other data that suggests or demonstrates that people who are in these sort of suicidal depressive episodes have the highest lifetime risk of completing a suicide attempt after they get discharged from their first inpatient hospital stay for a mood disorder," Williams said.

"The No. 1 risk for suicide is previous suicide attempt. The No.

2 risk for suicide is hospitalization prior to that attempt." Williams said he became convinced that something like this was needed. TMS in its current, U.S. Food and Drug Administration-approved form works over a longer period of time, about six weeks, so it is not as useful to someone who will only be an inpatient on a suicide hold for about 10 days.

SAINT works more quickly. About half the patients who have standard TMS improve, and one-third experience remission from depression. "We figured out a way to compress an entire six-week course of TMS into a single day.

And so then we're able to give five times as much stimulation, and there's a bunch of new neuroscience, basically, in how to rearrange those pulses in time and in space," Williams explained. The patients in the study ranged from 22 to 80, with an average of nine years of depression. They had tried medications, which either had no effect or had stopped working over time.

Four weeks after treatment, 12 of the 14 participants who received the real treatment had improved, with 11 meeting FDA criteria for remission. Only two of the 15 people who received the placebo met the criteria for remission. QUESTION Depression is a(n) __________.

See Answer "To have something that can work very fast and can last for some people years, some people months, it's a pretty big jump as far as having some important tools in the tool belt for treating depression," Williams said. Compared to the conventional TMS treatment, this is also more individualized because of the MRI. "I think why this is working so much better is we're able to give [a] dose that's enough for that individual and we're able to do it in a personalized way," Williams said.

"If you can maintain this, it can put people back to work, it can get people back on track. They finally have the life that they want, so it can be a very dramatic improvement for folks if they can kind of get out of that mood episode," Williams said. "That's what we've seen with folks is that they're just kind of categorically in a better spot." Refining the brain stimulation process Van Brocklin's sister, who lives in California, had suggested the trial.

Van Brocklin, who lives in Tennessee, said he is working now to remember he's on a mission to stay well and giving up habits that were not working for him. "I'm feeling good. It's definitely stayed with me.

It didn't just vanish away," said Van Brocklin, who had the treatment in early September. The findings were published Oct. 29 in the American Journal of Psychiatry.

Dr. Mark George, known as a TMS pioneer for his work on the FDA-approved version of the treatment, reacted to the findings with enthusiasm. "Although the treatment itself is great, really very few side effects, there are no drug interactions, no cognitive side effects, no IVs.

The biggest drawback has really been the time intensiveness of it. It just took a lot of chair time to get people well," George said about conventional TMS. "And because it took a lot of chair time, it was pretty expensive or you can only treat so many patients in a day.

... That's been one of the things that's kind of held it back from being more useful. "This study is massively important because it shows convincingly, really without any doubt, that you can do what we used to do in six weeks, bigger, faster, better in a week," continued George, who is the Layton McCurdy Endowed Chair in Psychiatry at the Medical University of South Carolina.

These results are important because of the really high response and remission rates, he said. "Suicide rates in the United States have climbed year over year without really slowing down, even though we have widely available medications, and so having a tool that can quickly get people [out of suicidal thinking] would be very, very effective," George said. "As â¦ somebody who started this many, many years ago, it is really gratifying to see how, over time, hardworking doctors and scientists and patients who agree to be in these studies and work together to refine an entirely new way of treating illnesses in the brain and, with some clever thought and changes and then funding, really make breakthroughs," George said.

More information The U.S. Substance Abuse and Mental Health Services Administration offers a national helpline for people with depression and other mood disorders. SOURCES.

Nolan Williams, MD, assistant professor, psychiatry and behavioral sciences, Stanford University, and director, Stanford Brain Stimulation Lab, Stanford, Calif.. Mark George, MD, Layton McCurdy Endowed Chair in Psychiatry, Medical University of South Carolina, Charleston. Tommy Van Brocklin, Memphis, Tenn..

From Depression Resources Featured Centers Health Solutions From Our Sponsors.

Latest Neurology News By Alan Mozes where to buy diuretic lasix HealthDay ReporterTHURSDAY, Oct. 28, 2021 (HealthDay News) -- The number of Americans who are dying from Parkinson's disease has jumped by 63% in the past two decades, new research shows. The fresh analysis also revealed that where to buy diuretic lasix men face double the risk of dying from the progressive and incurable disease than women.

According to the Michael J. Fox Foundation, Parkinson's affects roughly 1 million Americans and more than 6 million people around the world. To get a handle on trends among Parkinson's patients, Bao and his where to buy diuretic lasix colleagues analyzed data collected by the U.S.

National Vital Statistics System. The team found that nearly 480,000 Americans died of Parkinson's between 1999 and 2019. During that time, the risk of dying from Parkinson's rose year after year by an average of 2.4%, with a significant increased risk seen among both men and where to buy diuretic lasix women of all ages and ethnicities, and across both urban and rural locales, and in every state in the nation.

That steady rise translated into nearly nine out of every 100,000 Americans succumbing to Parkinson's by 2019. That figure is notably up from a little more than five Parkinson's deaths for every 100,000 Americans just 20 years earlier. While risk went up across the board, men appeared to be much where to buy diuretic lasix more vulnerable than women, the findings showed.

By 2019, the death rate among men was pegged at double that of women. One possible reason why. Higher levels of estrogen in women may ultimately bolster motor control, the investigators said, and shield women from developing Parkinson's where to buy diuretic lasix.

Death rates were also cited as being highest among white patients (9.7 per 100,000 people), followed by Hispanics (6.5 per 100,000) and Black people (4.7 per 100,000). The team cautioned, however, that some of that differential might reflect higher diagnosis rates among whites due to greater access to neurology care. As to what might be driving up death rates overall, the study authors stressed that their research did not set where to buy diuretic lasix out to identify cause, with Bao acknowledging that "the reason is not clear at present and warrants further investigation." But the team theorized a number of possibilities.

On the one hand, a higher death rate among Parkinson's patients may be at least partially linked to a rising risk for developing Parkinson's in the first place. And investigators pointed to a variety of reasons Parkinson's may be becoming more common, including worsening environmental factors such as elevated exposures to pesticides, heavy metals, air pollution and herbicides. Improved accuracy on precise cause of where to buy diuretic lasix death (as noted on death certificates) may also have played a role, the investigators added.

Still, James Beck, chief scientific officer for the Parkinson's Foundation, said the findings "are not surprising." The foundation has also observed that the number of people with Parkinson's has risen, and "will continue to rise as the population ages, so an increase in mortality rates would be expected," he noted. Beck said that improved diagnostics is what accounts for much of the rising death rates, as doctors become more adept at recognizing Parkinson's, "which would lead to higher rates of identifying PD [Parkinson's disease] as a cause of death." Regardless, Dr. Rachel Dolhun, senior vice where to buy diuretic lasix president of medical communications at the Michael J.

Fox Foundation, suggested that while "more data is needed to better understand these trends," Parkinson's patients should not be discouraged by the numbers. "If you're a person or family living with PD, I where to buy diuretic lasix understand how a headline like this could be scary," she said. "But the bottom line is that these types of studies are helping us direct more resources and research so that we can learn more about the disease and its impact on the community, develop better treatments and a cure and, ultimately, prevent Parkinson's." Meanwhile, "I often tell people â especially those newly diagnosed â that your Parkinson's is your Parkinson's.

Your symptoms, how they change over time, and how they impact your life are all unique to you," Dolhun added. "The individualized nature of the disease can make it difficult where to buy diuretic lasix to predict progression and symptoms in any one person." So, she said, the goal is "to manage the disease and live as well as possible," through a combination of diet, exercise and good physician guidance, because "for many, Parkinson's doesn't significantly shorten lifespan." More information There's more on Parkinson's at the Michael J. Fox Foundation.

SOURCES. Wei Bao, MD, PhD, associate professor, department of epidemiology, College of Public Health, University where to buy diuretic lasix of Iowa, Iowa City. James Beck, PhD, chief scientific officer, Parkinson's Foundation, Miami.

Rachel Dolhun, MD, senior vice president, medical communications, Michael J. Fox Foundation, New where to buy diuretic lasix York City. Neurology, Oct.

Alzheimer's Disease and Aging Brains See SlideshowLatest Women's Health News By Cara Murez HealthDay ReporterTHURSDAY, Oct. 28, 2021 (HealthDay News) where to buy diuretic lasix Might breastfeeding affect a new mother's future brain health?. That's the intriguing question posed by a new study that flips the narrative from the often-touted benefits for baby to what impact breastfeeding might hold for Mom years later.

Researchers from UCLA Health found that women over age 50 who had breastfed their babies performed better on tests of brain function than those who had not. "The findings were pretty straightforward in that we compared women who did versus did not breastfeed," said where to buy diuretic lasix lead author Molly Fox, an assistant professor in the Departments of Anthropology and Psychiatry and Behavioral Sciences at the University of California at Los Angeles. And women who did performed better on tests of thinking and memory skills, also known as cognition.

The findings are significant because impaired cognition after age 50 can be a strong predictor of Alzheimer's disease, the leading form of dementia and cause of disability in the elderly. About two-thirds of Americans with where to buy diuretic lasix Alzheimer's are women. "We repeated the analyses looking only at women who had children to make sure that we weren't just picking up an effect of whether or not you had children and the results were the same," Fox said.

"It does seem to be that there was something connected to breastfeeding specifically, and not just whether or not you have kids." The study included 115 women who were part of two 12-week clinical trials at UCLA Health. Sixty-four described themselves as depressed, and where to buy diuretic lasix 51 as not depressed. All completed a questionnaire about their reproductive life history, including the age they began their period, number of pregnancies, length of time they breastfed for each child and their age at menopause.

The women also completed psychological tests that measured brain function in four areas. Learning, delayed recall, where to buy diuretic lasix executive functioning and processing speed. None had been diagnosed with dementia.

In all, where to buy diuretic lasix 65% of women who said they were not depressed had breastfed, compared to about 44% of women with depression. Whether they described themselves as depressed or not, women who had breastfed performed better in tests of all four brain functions evaluated compared to those who had not, the study found. All four scores were significantly linked to breastfeeding in women without depression.

But only two were strongly associated with breastfeeding in the group with depression -- processing speed and executive function, which includes where to buy diuretic lasix skills such as flexible thinking, self-control and working memory. Women who had not breastfed had significantly lower scores in three of the four brain functions evaluated compared to women who had breastfed for one to 12 months. Additionally, their scores were lower in all four areas compared to women who breastfed for more than a year.

What's unique about breastfeeding Though the researchers weren't able to directly where to buy diuretic lasix examine what's connecting the two, they have some theories. "I think it would make sense that there are some things that we know breastfeeding affects, like a woman's energy metabolism, lipid metabolism, and these are systems that are already implicated in brain aging and Alzheimer's risk," Fox said. The intriguing -- and exciting -- possibility is that breastfeeding could exert effects on metabolism or other bodily functions that could be responsible for the pattern researchers saw.

"To address where to buy diuretic lasix the question about what it means for women who did or did not have kids, the story is much more complex than the scientific study, because the actual lived experience in women's reproductive histories involves so many different phases and systems and we were only looking at this one factor," Fox said. She noted that the study shows an association and doesn't prove cause and effect. QUESTION Newborn babies don't sleep very much.

See Answer The link might not even have a biological cause, Fox said, but might owe to the psychological or social experience of bonding with your child or where to buy diuretic lasix the family dynamics around breastfeeding. Dr. Neelum Aggarwal, a fellow of the American Academy of Neurology and associate professor at Rush Medical College in Chicago, reviewed the findings.

"This is where to buy diuretic lasix an interesting study as it expands our thinking about a woman's reproductive history and relatedness to cognitive decline and dementia," she said. But more study is needed, Aggarwal said. Multiple factors and issues in society, including concerns about mood, depression, anxiety and how they may limit breastfeeding, should be investigated in a larger, diverse population, she said.